Every day, millions of patients are told “everything looks normal” — even when they know something is wrong.
Physio PS exists to change that.
Our Story
“Physio PS uncovered a life-threatening heart condition my cardiologist completely missed.
I had no symptoms — just luck that I took the test.
Knowing how many people die from silent conditions like this every day, I took over the company to make sure others get the same chance I did.”
— Steve O’Leary, CEO, Physio PS
Physio PS was built to bridge the gap between
what traditional medicine sees and
what the body actually communicates.
We make the invisible measurable — uncovering root causes behind chronic, unexplained conditions that cost lives and billions in preventable healthcare spending.
The Problem
90+ million Americans suffer silently from autonomic nervous system (ANS) dysfunction.
Yet no standard medical test can measure how the sympathetic and parasympathetic systems — the body’s automatic control centers — are functioning.
This gap in diagnostics leads to:
Misdiagnosis of chronic conditions
Unnecessary prescriptions
Missed opportunities for early intervention
Billions in preventable healthcare costs annually
Our Solution — Physio PS Technology
Delivering AI-powered physiological insight to clinics, hospitals, and research centers globally.
Patented. AI-driven. Clinically validated.
Physio PS is the only FDA-cleared technology that measures both branches of the autonomic nervous system independently and simultaneously, in real time.
Using a 3-lead ECG, blood pressure cuff, and heart rate sensor, Physio PS delivers a 15-minute, non-invasive test that:
Detects hidden dysfunctions early
Differentiates between root causes
Empowers clinicians with actionable insights
“No other technology measures the nervous system like Physio PS.”
— Dr. Howard Snapper, MD, Cardiovascular Disease Specialist
The Autonomic Nervous System
The Sympathetic Nervous System
Know as your fight and flight response control the following involuntary functions:
> Vagal Nerve Inhibited
> Dilates Pupils
> Inhibits Salvation
> Increases Heart Rate
> Bronchial Dilation
> Inhibits Digestion
> Stimulates Glucose Release
> Inhibits Intestine Activity
> Secretes Epinephrine & Norepinephrine
> Releases Bladder
> Ejaculation
> Peripheral Vasoconstriction
The Parasympathetic Nervous System
Know as your rest and digest response control the following involuntary functions:
> Vagal Nerve Activated
> Constricts Pupils
> Stimulates Salivation
> Decreases Heart Rate
> Bronchial Constriction
> Stimulates Digestion
> Stimulates Gallbladder
> Stimulates Intestine Activity
> Contracts Bladder
> Vaginal Lubrication
> Erection
> Peripheral Vasodilation
Market Opportunity
Physio PS is positioned at the intersection of AI diagnostics, digital healthcare, preventative care, precision health, and clinical care diagnostics — a rapidly growing $100+ Billion global opportunity.
The future of healthcare lies in data-driven prevention and precision diagnostics.
$4.5 Trillion U.S.
healthcare market — 80% tied to chronic conditions.
$30+ Billion Annual
cost in “medically unexplained symptoms.”
90+ Million
Over 90 million Americans suffer silently from ANS imbalance.
Expanding
demand for preventive and personalized medicine diagnostics.
Scalable
SaMD model for clinics and healthcare networks.
Recurring
revenue through revenue sharing, software licensing and data licensing.
Investment Highlights
Proprietary, Patented Technology – The only system measuring both ANS branches simultaneously.
High ROI for Clinics – Scalable returns with even modest testing volume.
Rapidly Expanding Market – Global diagnostics and preventive care sectors growing >9% CAGR.
AI + SaMD Expansion – Scalable data monetization and predictive analytics opportunities.
Clinical Adoption – Implemented across a wide range of medical and wellness practices global.
Data Licensing – Tens of thousands of clinical tests captured for use in AI, a tremendous AI Data licensing model
We currently offer three system configurations for administering ANS function testing.
Solutions Simplified For All
Clinical Monitoring Unit
The perfect addition to any clinic
Offer your patients greater insight
Enhance preventive health measures
The Best ANS Test increases revenue
Many purchase options
FDA 510(k) Cleared
Supported by fundable billing codes
Research options available
Remote Monitoring Unit
Bring The Best ANS Test on the go
Improve quality of life
Compact and Convenient
Operates with battery power
The Best ANS Test increases revenue
Great for in-home care providers
Perfect for sports medicine
Many purchase options
Portable Autonomic Lab
Portable & deployable
Prefect for the clinician on the go
The Best ANS Test available anywhere
Multiple power options
Compact and convenient
Offer patients more personalized care
Wearable Autonomic Lab
Coming soon!
Portable & deployable
The Best ANS Test available anywhere
Compact and convenient
Real Impact: Veteran Affairs Case Study
At the Atlanta VA, a 26-year-old Navy SEAL was misdiagnosed for years.
Traditional tests failed. Physio PS identified the root cause — Vasovagal Syncope — in minutes.
Within weeks, he regained mobility.
Within months, he returned to full health.
Within a year, he was medication-free.
Join the Movement
We’re building the next generation of medical diagnostics — where discovery, diagnosis, and recovery are connected through data.
Invest in the technology that’s redefining preventive medicine.
Testimonials
Sean O. Flannagan
PT, DPT, Cert. SMT, Cert. DN, MAACP
Physio PS has been a gamechanger in uncovering the hidden autonomic dysfunctions that often underlie chronic fatigue, persistent pain, anxiety symptoms, and delayed recovery after whiplash and concussion. It’s given us answers when nothing else could — and a clear path to true healing.
Heather Bloom
MD, FACC, Director of Cardiac Electrophysiology, Atlanta VAMC Associate Professor, Emory University School of Medicine
As a VA Electrophysiologist, I’ve used ANSAR’s Parasympathetic and Sympathetic Monitoring for years with outstanding results. It delivers diagnostic insights no other tool can provide. One case—a Navy SEAL suffering from severe dizziness and disability—was accurately diagnosed and effectively treated using ANSAR technology, after traditional tests failed. The patient regained his health, quality of life, and independence. This tool is a game-changer for patient care and healthcare efficiency.
Michael Stopyra
I cannot say enough good things about Physio PS! This technology has done so much for me. I used to have terrible anxiety storms that would cause me to have high fevers. With this simple test, my doctor was able to find the root cause of my symptoms and prescribe a very low-dose medicine for about nine months to correct the primary problem. I have not had a high fever in four years!
Letters of Recommendation
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The material and information provided by Physio PS is for general information purposes only. You should not rely upon this material or information for basis of making healthcare, treatment, or diagnosis decisions. While Physio PS strives to provide the most correct and up-to-date information and data, Physio PS makes no representations or warranties of any kind, expressed or implied, about the completeness, accuracy, reliability, suitability, or availability with respect to the information, products, services, or related graphics contained. Any reliance placed on such material is therefore strictly at your own risk. Reporting Information is supplied under license by NCRC LLC. * ‘RFa’ is known to be a measure of Parasympathetic activity and ‘LFa’ is known to be a measure of Sympathetic activity, based on reference: Colombo J, Arora RR, DePace NL, Vinik AI, Clinical Autonomic Dysfunction: Measurement, Indications, Therapies, and Outcomes. Springer Science + Business Media, New York, NY; 2014.
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